The Incubator
The Incubator
Ben Courchia & Daphna Yasova Barbeau
#469 - [Journal Club] - 📌 What did two Dutch NICUs learn from routine probiotics in preterm infants?
22 minutes Posted Sep 30, 2026 at 6:00 am.
0:00
22:15
Download MP3
Show notes
Send us Fan Mail In this Journal Club episode, Ben reviews a JAMA Network Open study from two Dutch Level IV NICUs. It examined NEC before and after routine implementation of a three-strain probiotic in 1,413 infants born before 30 weeks or under 1,000 grams. NEC fell from 11.9% to 5.3%, and late-onset sepsis also declined. But non-NEC mortality rose after implementation. NEC also dropped in an unexposed reference cohort, and one infant died of B. infantis sepsis. Ben and Daphna discuss how b...