The Incubator
The Incubator
Ben Courchia & Daphna Yasova Barbeau
#453 - [Journal Club] - 📌 Should We Treat the PDA Based on Size Alone? (SMART PDA Trial)
43 minutes Posted Jul 13, 2026 at 6:00 am.
0:00
43:47
Download MP3
Show notes
Send us Fan Mail In this Journal Club, Ben and Daphna dig into two new papers on PDA management in our smallest patients. First, the SMART-PDA pilot RCT from Souvik Mitra and colleagues, which uses comprehensive hemodynamic screening to selectively treat high-volume shunts in infants born before 26 weeks, and whose striking Bayesian signal for reduced pulmonary hemorrhage and NEC stopped the trial early. Then a companion JAMA Network Open comparative effectiveness study across four pharmacoth...