I discussed this in many of my videos, the need for a database that natively supports a multiplexing protocol such as QUIC, gRPC or HTTP/2 in order to allow multiple isolated clients to make requests to the database without taking the overhead of establishing multiple connections.   

Resources https://www.infoq.com/news/2021/01/eventstoredb/ https://developers.eventstore.com/clients/dotnet/5.0/streams/#writing-to-a-stream