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In this episode, I explain how nicotine impacts the brain and body, including its potent ability to enhance attention, focus, and alertness, increase blood pressure and metabolism and reduce appetite. I discuss nicotine’s ability to increase the action of neurochemicals, including dopamine, norepinephrine, and acetylcholine and activate sympathetic (alertness-promoting) neural circuits. I also discuss common nicotine delivery methods, such as cigarettes, vaping, dip, and snuff, and how they each create their own unique experience and how they, but not nicotine itself, cause cancer and other adverse health effects. I also explain science-based tools to permanently quit smoking cigarettes or vaping, including peer-reviewed clinical hypnosis tools, antidepressants, and alternative nicotine replacement (patches, lozenges, gums etc.). As nicotine is one of the most widely used substances with billions of users — most of whom report wanting to quit — this episode ought to be of interest to former/current nicotine users, those who want to quit smoking or vaping and/or those interested in learning the biology behind how nicotine impacts the brain and body.
For the full show notes, visit hubermanlab.com.
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Timestamps
(00:00:00) Nicotine
(00:03:41) Tool: Brief Daily Meditation & Focus
(00:05:59) The Arrow Model of Focus, Alpha GPC & Garlic Supplements
(00:10:05) Sponsor: LMNT
(00:14:35) Nicotine Effects vs. Methods of Delivery, Acetylcholine
(00:19:55) Where is Nicotine Found? Nicotinic Acetylcholine Receptors
(00:25:12) Nicotine & Effects on the Brain: Appetite, Dopamine & GABA
(00:29:37) Sponsor: AG1
(00:32:11) Nicotine, Acetylcholine & Attentional “Spotlighting”
(00:37:29) Nicotine, Norepinephrine & Alertness/Energy
(00:41:10) Nicotine & Effects on Appetite & Metabolism
(00:46:47) Nicotine & Effects on Body: Sympathetic Tone
(00:51:29) Nicotine & Cognitive Work vs. Physical Performance
(00:55:08) Nicotine Delivery Methods & Side Effects, Young People & Dependency
(00:58:35) Smoking, Vaping, Dipping & Snuffing: Carcinogens & Endothelial Cells
(01:02:34) Smoking, Vaping, Dipping & Snuffing: Negative Impacts on Lifespan & Health
(01:09:23) How to Quit Smoking, Nicotine Cravings & Withdrawal
(01:13:56) Vaping & Nicotine, Rates of Effect Onset, Dopamine, Addiction & Depression
(01:25:06) Tool: Quitting Smoking & Clinical Hypnosis, Reveri
(01:30:16) Bupropion (Wellbutrin) & Quitting Smoking
(01:36:24) Tool: A Nicotine Replacement Schedule to Quit Smoking, Nicotine Patch/Gum
(01:41:52) Tool: Biological Homeostasis & Nicotine Withdrawal, The “First Week” Strategy
(01:51:39) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook
Title Card Photo Credit: Mike Blabac
Disclaimer

Nicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping

Narrator: Abbe Opher 🇬🇧
Writer: Alicia ✍️
Sound design: harbour ambience 🛳
 
Welcome back, sleepyheads. Tonight, we return to the rugged coastline of Maine, with our protagonist, Emma. This time, she makes her way to the Rockland Breakwater Light. 😴 
 

👀 Watch, listen and comment on this episode on our new Get Sleepy YouTube channel!
And hit subscribe while you're there!
 

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About Get Sleepy 
Get Sleepy is the #1 story-telling podcast designed to help you get a great night’s rest. By combining sleep meditation with a relaxing bedtime story, each episode will guide you gently towards sleep. 

 
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Get your 7-day free trial: https://getsleepy.com/support. 
 
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That’s all for now. Sweet dreams ❤️ 😴
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Get Sleepy: Sleep meditation and stories

Tales of the Rockland Breakwater Light

Our story tonight is called The Pecan Tree and it’s a story about having just the right tool for the right moment. It’s also about a piano playing in a neighbor’s house, gravel paths in a garden and an afternoon visit from a few friends at the split rail fence.

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The Pecan Tree

This episode is brought to you by Rupa Health, InsideTracker, and Cozy Earth.
If you’ve ever wondered if supplements are worthwhile or just create expensive urine, this is the podcast episode for you. While I wish it wasn’t the case, I do believe we need supplements to make up for the nutrients we can no longer get through food alone. It’s extra important to note, though, that not all supplements are created equal. And please keep in mind they’re called “supplements” for a reason, not “replacements”—they are meant to supplement a healthy diet and lifestyle to provide the most impact.
Today, I’m excited to take a deeper dive into this topic with one of my most trusted sources when it comes to nutrition and dietary research, Chris Kresser. Chris Kresser M.S., L.Ac. is the co-founder of the California Center for Functional Medicine, the founder of Kresser Institute, the host of the top-ranked health podcast Revolution Health Radio, the creator of ChrisKresser.com, and the New York Times best-selling author of The Paleo Cure and Unconventional Medicine. Chris is one of the most respected clinicians and educators in the fields of Functional Medicine and ancestral health and has trained over 2,000 clinicians and health coaches from over 50 countries in his unique approach. He has recently launched Adapt Naturals, a supplement line designed to add back in what the modern world has squeezed out and help people perform and feel their best.
This episode is brought to you by Rupa Health, InsideTracker, and Cozy Earth.
Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.
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Here are more details from our interview (audio version / Apple Subscriber version):

Do we really need to take supplements? (5:14 / 1:54) 

Why our food is less nutritious than it used to be (13:32 / 10:10) 

Can you really get your nutrients from food? (15:28 / 12:10) 

The prevalence of, and most common, nutritional deficiencies (16:27 / 13:35) 

Testing your nutrient levels (21:35 / 18:25)

Symptoms of common nutrient deficiencies (29:03 / 25:05) 

Can you take too much or overdose on nutrients? (41:57 / 36:58) 

What to look for in a quality vitamin or supplement (51:37 / 47:10) 

What nutrients are provided by plant vs animal foods (59:41 / 55:06)  

The most nutrient-dense foods (1:10:23 / 1:05:45) 


Learn more about Chris at ChrisKresser.com and check out his new supplement line, Adapt Naturals.

 
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Why Most Of Us Are Nutrient Deficient And What To Do About It with Chris Kresser

Today I sit down with the very amazing Noah Cyrus. Noah is a Grammy award-nominee, multi platinum, Nashville-born and Los Angeles-based singer and songwriter. Emerging in 2016 at the age of 16, she immediately captivated audiences with platinum singles "Make Me (Cry)" and Again. Noah teamed up with PJ Harding for the People Don't Change EP in 2021. Along the way, she performed at Coachella twice, while Billboard named her among its "21 Under 21" for three straight years. She also shined on The Late Late Show with James Corden, The Tonight Show Starring Jimmy Fallon, Ellen, and The Today Show. Now, she introduces the next chapter with the "I Burned LA Down".

Noah shares to us a vulnerable side of her and how music has helped her heal from her past. Growing up she mentioned that self-love and self-acceptance was something that she never really practiced and is still a difficult thing to do at the present but she is a work in progress and even though life is full of ups and downs, she is moving forward. We also exchanged our thoughts on why change is inevitable for people and how we can be comfortable with it. Noah herself experienced a life changing experience and I am so honored to hear her story.

Noah Cyrus ON: How to Handle Negative Opinions of Others & Turning Anxiety into Creativity

In this episode, we talk with:
- A woman wrestling with resentment toward her therapist husband. (1:44)
- A wife unable to trust her financially irresponsible husband. (20:50)
- A man coming to terms with the extent of his anger issues. (36:05)

Lyrics of the Day: "Burning Down The House" - Talking Heads
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My Husband Can Be So Condescending

Narrator: Simon Mattacks 🇬🇧
Writer: Shady Grove ✍️
Sound design: city ambience, gentle river 🏙 🌊
 
Welcome back, sleepyheads. We know you've enjoyed our other sleepy history episodes, so tonight, we have another soothing historical exploration. We’ll trace the origins of Oktoberfest and see how it’s changed over time to become one of the most popular festivals in the world. 😴 
 
👀 Watch, listen and comment on this episode on the Get Sleepy YouTube channel! And please hit subscribe while you're there!
 

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Connect 
Stay up to date on all podcast news and even vote on upcoming episodes! 
- Website: https://getsleepy.com/. 
- Facebook: https://www.facebook.com/getsleepypod/. 
- Instagram: https://www.instagram.com/getsleepypod/. 
- Twitter: https://twitter.com/getsleepypod. 

 
About Get Sleepy 
Get Sleepy is the #1 story-telling podcast designed to help you get a great night’s rest. By combining sleep meditation with a relaxing bedtime story, each episode will guide you gently towards sleep. 

 
Get Sleepy Premium
Get instant access to ad-free episodes, as well as the Thursday night bonus episode by subscribing to our premium feed. It's easy! Sign up in two taps! 
Get Sleepy Premium feed includes: 

Monday and Wednesday night episodes (with zero ads).

The exclusive Thursday night bonus episode.

Access to the entire back catalog (also ad-free).

Exclusive sleep meditation episodes.

Discounts on merchadise.

We’ll love you forever.

Get your 7-day free trial: https://getsleepy.com/support. 
 
Thank you so much for listening! 
Feedback? Let us know your thoughts! https://getsleepy.com/contact-us/.  
That’s all for now. Sweet dreams ❤️ 😴
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The Sleepy History of Oktoberfest

In this episode of Quah (Q & A), Sal, Adam & Justin coach four Pump Heads via Zoom.  Mind Pump Fit Tip: If you’re going to go vegan, do it for the RIGHT reasons. Otherwise, it’s likely to lead to worse health. (2:54) Things that Adam finds cool. (10:22) The brain blend from Ned is FIRE!! (17:13) Mind Pump on the controversy surrounding Andrew Tate and the dangers of censorship. (18:50) A clear example of obsessive fandom. (41:13) Remembering Bill Pearl. (44:54) The sex-tape formula for success. (48:19) ‘Buy My House’, the Shark Tank for real estate. (50:49) The meat sticks from Paleo Valley are a HIT with the kids. (52:54) Canada’s twisted law. (56:08) #ListenerLive question #1 - How can I measure if I am out of symmetry, and how can I improve it? (1:01:26) #ListenerLive question #2 - How can I stay satiated during Dr. Cabral’s 4-month Sibo protocol? (1:09:12) #ListenerLive question #3 - How do I program the right exercises to strengthen my lower back and core? (1:17:06) #ListenerLive question #4 - If you could design a template for extracurricular training for elementary, middle, and high school students that would span those years, where would you start and what would that template look like? (1:28:57)  Related Links/Products Mentioned  Ask a question to Mind Pump, live! Email: live@mindpumpmedia.com Visit NED for an exclusive offer for Mind Pump listeners! Visit Paleo Valley for an exclusive offer for Mind Pump listeners! **Promo code MINDPUMP15 at checkout for 15% discount** September Promotion: Skinny Guy Bundle (MAPS ANABOLIC // MAPS AESTHETIC // NO B.S. 6-PACK FORMULA // INTUITIVE NUTRITION GUIDE // OCCLUSION TRAINING GUIDE.) HALF OFF!! Also, the Fit Mom Bundle (MAPS ANYWHERE // MAPS ANABOLIC // MAPS HIIT // and INTUITIVE NUTRITION GUIDE.) HALF OFF!! **Code SEPT50 at checkout**  Debunking the vegan myth: The case for a plant-forward omnivorous whole-foods diet Dyson v15 detect Exclusive: Andrew Tate UNCENSORED Interview with Patrick Bet-David  Put it in the books! Ty Cobb's dentures auctioned for $18K+  Bill Pearl’s 1967 Mr. Universe Workout  Ray J Just Claimed That Kris Jenner Watched Multiple Different Sex Tapes Of Him And Kim Kardashian And Chose Which One To Release To The Public  Redfin CEO gets into real estate reality TV with spot on new Netflix show ‘Buy My House’ Watch Buy My House | Netflix Official Site  Some Canadian Health Care Patients Say They're Being Encouraged To Just Die Already Visit MASSZYMES by biOptimizers for an exclusive offer for Mind Pump listeners! **Promo code MINDPUMP10 at checkout** MAPS Symmetry  Mind Pump #1825: Man Cheats Death & Builds Cold Plunge Business Equi.life is offering all Mind Pump listeners an at-home Minerals & Metals At-Home Lab Test for 50% off!  MP Holistic Health Add Windmills to Your Workout to Increase Your Deadlift Strength – Mind Pump TV How To Do A Turkish Get-Up – Mind Pump TV How To Do The Sled Push The RIGHT Way! (AVOID MISTAKES!) – Mind Pump TV  MAPS Suspension Training  Mind Pump Podcast – YouTube Mind Pump Free Resources  People Mentioned  Patrick Bet-David (@patrickbetdavid) Instagram Derek (@moreplatesmoredates) Instagram Dr. Stephen Cabral (@stephencabral) Instagram Wim Hof (@iceman_hof) Instagram  

1906: How to Address Low Back Pain Related to Squatting & Deadlifting, Fixing Imbalances Between the Right & Left Side of the Body, How to Get Kids Started With Strength Training & More (Listener Live Coaching)

A woman discovered that her 80 year-old father has been downloading porn, and it’s mucking up his computer. She *could* teach him about Pornhub and other streaming sites. But her father already spends too much time in front of a computer, and really could use some exercise and contact with people. Will more porn just isolate him further? 
A dom man wants to do anal with his female sub. But she isn’t interested. How can he try to inspire her to be more game without invoking his dom status? 
On the Magnum, the interview with beloved monkey pox expert Dr. Carlton Thomas begins innocently enough. Cases are coming down, as more gay men get vaccinated. Then he and Dan veer into wilder territory, and you don’t want to miss it. 
A lesbian from Texas has a lot of tattoos. Is it too dangerous to send nudes when she can be so easily identified? 
Q@Savage.Love     206-302-2064


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Savage Lovecast

Savage Lovecast Episode 830

We talk about why we observe the birthday of our spiritual teachers, discuss the challenge of the “arrival fallacy,” share a hack about creating more kitchen counter space, and tackle a listener question about being a happiness bully.
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Happier with Gretchen Rubin is part of ‘The Onward Project,’ a family of podcasts brought together by Gretchen Rubin—all about how to make your life better. Check out the other Onward Project podcasts—Do The Thing, Side Hustle School, Happier in Hollywood and Everything Happens with Kate Bowler. If you liked this episode, please subscribe, leave a review, and tell your friends!
 
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Happier with Gretchen Rubin

Happier - Ep. 396: Observe the Birthday of a Spiritual Teacher, Plus the “Arrival Fallacy” and Happiness Bullies

Welcome to my NEW series "Awkward Therapy" with my good friend Jay Shetty, who is an award winning host, storyteller and viral content creator. In this series, we are aiming to discuss different taboo topics in an effort to create a comfortable dialogue.

5 Relationship Mistakes You Must Avoid to Find Deeper Connection w/ Jay Shetty [AWKWARD THERAPY] EP 1322

Narrator: Thomas Jones 🇬🇧
Writer: Davenport ✍️
Sound design: distant waves, birdsong 🌊🐦
 
Welcome back, sleepyheads. Tonight’s story is all about the simple pleasure of walking. We’ll go for a stroll through a peaceful neighbourhood near the sea and end the day watching a magical sunset over the ocean. Then, you’ll head home to your beach cottage. 😴 
 
👀 Watch, listen and comment on this episode on the Get Sleepy YouTube channel! And hit subscribe while you're there! :)
 

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Connect 
Stay up to date on all podcast news and even vote on upcoming episodes! 
- Website: https://getsleepy.com/. 
- Facebook: https://www.facebook.com/getsleepypod/. 
- Instagram: https://www.instagram.com/getsleepypod/. 
- Twitter: https://twitter.com/getsleepypod. 

 
About Get Sleepy 
Get Sleepy is the #1 story-telling podcast designed to help you get a great night’s rest. By combining sleep meditation with a relaxing bedtime story, each episode will guide you gently towards sleep. 

 
Get Sleepy Premium
Get instant access to ad-free episodes, as well as the Thursday night bonus episode by subscribing to our premium feed. It's easy! Sign up in two taps! 
Get Sleepy Premium feed includes: 

Monday and Wednesday night episodes (with zero ads).

The exclusive Thursday night bonus episode.

Access to the entire back catalog (also ad-free).

Exclusive sleep meditation episodes.

Discounts on merchadise.

We’ll love you forever.

Get your 7-day free trial: https://getsleepy.com/support. 
 
Thank you so much for listening! 
Feedback? Let us know your thoughts! https://getsleepy.com/contact-us/.  
That’s all for now. Sweet dreams ❤️ 😴
Learn more about your ad choices. Visit megaphone.fm/adchoices

A Slow Summer Walk

Do we even need to write a description? It&apos;s the Goopisode! Support us:Hear bonus episodes on PatreonDonate on PayPalGet Maintenance Phase T-shirts, stickers and moreLinks!How Goop’s Haters Made Gwyneth Paltrow’s Company Worth $250 MillionHow Gwyneth Paltrow took Goop from a homebrewed newsletter to a controversial $250 million wellness powerhouseGwyneth Paltrow Feels Good — and So Can YouIs Gwyneth Paltrow’s GOOP $1.6M In Debt?Goop and Condé Nast Team Up on a Magazine - The New York Times Gwyneth Paltrow didn&apos;t want Condé Nast to fact-check Goop articlesA hungry Gwyneth Paltrow fails the food-stamp challenge four days inDear Gwyneth, this is what living on food stamps really looks likeMy $29 Food Stamp Challenge &amp; The RecipesGwyneth Paltrow&apos;s Having the Chicest Yard Sale Ever Gwyneth Paltrow says children of celebrities &apos;almost have to work twice as hard&apos; once they &apos;unfairly&apos; get their start in Hollywood Gwyneth Paltrow brings aerial yoga, trans talks and cryofacials to Goop health conference We Attended Gwyneth Paltrow&apos;s $500-a-Ticket Health SummitAnti-Medication Goop Summit Expert Claims AIDS Treatment Kills and GMOs Cause DepressionInside Goop, Gwyneth Paltrow&apos;s Growing EmpireThe history of self-careStill Processing: We Care for Ourselves and Others in Trump’s AmericaThanks to Doctor Dreamchip for our lovely theme song!Support the show

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Kiran Krishnan is the chief microbiologist at Just Thrive with 17 years of experience in the dietary supplement and nutrition market. He comes from a strict research background, having spent several years with hands-on R&D in the fields of molecular medicine and microbiology at the University of Iowa. Full show notes: https://maxlugavere.com/podcast/252

The Genius Life

252: Leveraging Your Microbiome for Better Skin, Mood, and Brain Health, Plus Why Most Probiotics Suck | Kiran Krishnan and Tina Anderson

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Sleep With Me

1107 - Gold Stars and Bugles | Nuns in Space S3E5

In this episode, I discuss the physiological effects that drinking alcohol has on the brain and body at different levels of consumption and over time. I also describe genetic differences that predispose certain individuals to alcoholism, binge and habit-drinking. I explain alcohol metabolism in simple terms and how it effectively acts as a poison, leading to cellular stress and damage. I then explain that it impacts neuronal function and changes our thinking and behavior – hallmarks of inebriation. I also discuss how alcohol consumption of different amounts impacts inflammation, stress, neurodegeneration, and cancer risk and negatively impacts the gut microbiome, brain thickness, hormone balance, mood and feelings of motivation. Additionally, I discuss the biology of hangovers and describe science-based strategies to mitigate the severity of a hangover. Since alcohol is one of the most widely consumed recreational substances, this episode ought to be of relevance to everyone.  Indeed, even low-to-moderate alcohol consumption negatively impacts the brain and body in direct ways. The goal of this episode is to help people make informed decisions about their alcohol consumption that are in keeping with their mental and physical health goals. 
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Timestamps
(00:00:00) Effects of Alcohol Consumption
(00:03:19) Low to Moderate Alcohol Consumption & Neurodegeneration 
(00:06:14) Sponsors: AG1, LMNT
(00:10:46) Historical Context & Uses of Alcohol 
(00:13:28) Alcohol Metabolism, “Empty Calories” 
(00:18:23) Inebriation: Top-Down Inhibition, Impulsivity & Memory Formation
(00:24:23) Long-Lasting Effects & Impulsivity, Neuroplasticity & Reversibility 
(00:27:55) Food & Alcohol Absorption
(00:30:07) Alcohol & Serotonin, SSRIs & Depression, Risk for Alcoholism, Blackouts
(00:37:39) Predisposition for Alcoholism; Chronic Consumption, Cortisol & Stress
(00:43:29) Sponsor: AG1
(00:46:07) Genetic Predisposition for Alcoholism, Consuming Alcohol Too Young
(00:52:27) Gut-Liver-Brain Axis: Alcohol, Gut Microbiome, Inflammation & Leaky Gut 
(00:59:46) Tool: Improving/Replenishing Gut Microbiome 
(01:02:44) Reducing Alcohol Consumption & Stress 
(01:04:25) Hangover: Alcohol & Sleep, Anxiety, Headache
(01:12:11) Hangover Recovery, Adrenaline & Deliberate Cold Exposure 
(01:17:16) Hangover Recovery, Dehydration & Electrolytes
(01:20:45) Types of Alcohol & Hangover Severity, Congeners  
(01:25:25) Alcohol Tolerance, Dopamine & Serotonin, Pleasure-Pain Balance   
(01:33:36) Are There Any Positive Effects of Alcohol?, Resveratrol 
(01:35:42) Alcohol & Brain Thickness 
(01:37:11) Alcohol & Cancer Risk: DNA Methylation, Breast Cancer Risk 
(01:44:31) Mitigating Cancer Risk, Folate, B Vitamins 
(01:46:54) Alcohol & Pregnancy, Fetal Alcohol Syndrome 
(01:50:58) Hormones: Testosterone & Estrogen Balance
(01:55:09) Negative Effects of Alcohol Consumption 
(01:58:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips
Title Card Photo Credit: Mike Blabac
Disclaimer

What Alcohol Does to Your Body, Brain & Health

Welcome to Season 5 of Chasing Life, where we’ll explore the five traditional senses – sight, hearing, taste, touch and smell -- and beyond. To kick off the season, Dr. Sanjay Gupta talks to award winning science journalist Ed Yong about his new book “An Immense World, How Animal Senses Reveal the Hidden Realms Around Us.” Ed explains how all creatures live in their own “sensory bubble” through which they experience a sliver of reality. Plus, he takes us on a wild journey through the animal kingdom’s many mysterious senses that exist beyond the reach of what we humans can know. If you’ve ever wondered what it might be like to be a dog, a bat or an electric eel, you won’t want to miss this conversation.
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Chasing Life

Making Sense of Our World

In this episode Sal, Adam & Justin cover nine hacks that are critical for fat loss success without needing to count calories.

1907: Nine Ways to Get Lean Without Counting Calories

Our story tonight is called “Sleeping Weather” and it’s a story about a break from the heat and humidity. It’s also about the view from the porch swing at night, deer walking quietly through the corn fields and clearing your mind with paper and pen and end of the day.
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