“No matter what I do, I can’t seem to lose weight,” writes this week’s house call, who is also an Eat Fat, Get Thin challenge participant. “I think I’m cursed with a slow metabolism.”I hear this often among patients, and the good news is that no, you’re not cursed and yes, you can fix your metabolism.It’s important to remember that you are unique: Everyone was born with a different biochemical make-up. You have trillions of little energy factories called mitochondria that provide the fuel to run everything in your body. If you can remember high school biochemistry class, you know mitochondria convert the oxygen you breathe and the food you eat into energy for your body to use.Think of mitochondria as little combustion engines. When scientists talk about metabolism, they often refer to mitochondria. Effective mitochondria mean your body efficiently burns calories and you have a fast metabolism. Ineffective mitochondria don’t burn calories and slow down your metabolism.