2 Docs Talk: The podcast about healthcare, the science of medicine and everything in between.
2 Docs Talk: The podcast about healthcare, the science of medicine and everything in between.
Kendall Britt, MD and Amy Rogers, MD
Ep 25: Cholesterol and Heart Disease: What We Don't Know
12 minutes Posted May 2, 2016 at 12:00 am.
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Show notes

Because individuals with high cholesterol levels often develop

heart disease, we've come to accept that high cholesterol -
especially "bad" cholesterol, or LDL - causes heart disease.

But it can't be said often enough that correlation does not

equal causation, and it is beginning to look more and more like a
causal realtionship between cholesterol and heart disease just
isn't there. 

In this episode we talk about the status of treating cholesterol

to prevent heart disease and about a drug trial that punctuates the
whole process with a giant question mark. 

Take a listen and see what you think.

Resources:

"http://www.thennt.com/nnt/statins-for-heart-disease-prevention-without-prior-heart-disease/">
Number Needed to Treat with Statins for Primary Prevention

"http://www.thennt.com/nnt/statins-for-heart-disease-prevention-with-known-heart-disease/">
Number Needed to Treat with Statins for Secondary
Prevention

"http://www.thecardiologyadvisor.com/acc-meeting-highlights/evacetrapib-did-not-reduce-cv-events-in-high-risk-patients/article/487228/">
Evacitrapib Study Stopped Because of Clinical Futility

"http://news.heart.org/doctor-discussion-is-key-for-cholesterol-treatment/">
American Heart Association Guidelines for Prevention with
Statins